Toskani - Bioregenerative aesthetics

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ToskaniMed - Bioregenerative aesthetic medecine

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    Skin Architect Fillers

    Facial fillers with cross-linked hyaluronic acid
    For professional use only

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    Sterile, pyrogen-free injectable gels, composed of cross-linked sodium hyaluronate of non-animal origin in phosphate-buffered saline solution.

    Administration by authorized healthcare professionals.

    The unique Hyasep technology preserves the structure of very high molecular weight hyaluronic acid (3000 KDa) throughout the manufacturing process, preventing its thermal degradation. This ensures that its unique properties and benefits are maintained. Resulting in:
    Maximum biocompatibility:
    It is the hyaluronic acid most similar to the one naturally found in our skin.
    Maximum biocompatibility:
    It is the hyaluronic acid most similar to the one naturally found in our skin.
    Bio-stimulation and tissue regeneration:
    Ability to act at the level of fibroblasts and adipocytes, promoting tissue regeneration.
    Bio-stimulation and tissue regeneration:
    Ability to act at the level of fibroblasts and adipocytes, promoting tissue regeneration.
    Collagen and elastin stimulation:
    Maximum capacity to induce the synthesis of elastin and collagen, restoring the architecture of the extracellular matrix.
    Collagen and elastin stimulation:
    Maximum capacity to induce the synthesis of elastin and collagen, restoring the architecture of the extracellular matrix.
    Balanced duration of the result:
    Prolonged effect with a time-compensated duration.
    Balanced duration of the result:
    Prolonged effect with a time-compensated duration.
    Ultrapure hyaluronic acid:
    Obtaining a highly purified AH thanks to its unique characteristics, optimizing its quality and clinical profile.
    Ultrapure hyaluronic acid:
    Obtaining a highly purified AH thanks to its unique characteristics, optimizing its quality and clinical profile.
    Low crosslinking and high security:
    Very low degree of crosslinking along with minimal levels of BDDE, ensuring an excellent safety profile.
    Low crosslinking and high security:
    Very low degree of crosslinking along with minimal levels of BDDE, ensuring an excellent safety profile.
    Long-term security and stability:
    High long-term sustainability with reduced risk of late complications such as migration, nodules, or granulomas.
    Long-term security and stability:
    High long-term sustainability with reduced risk of late complications such as migration, nodules, or granulomas.
    Developed according to high standards of quality and purity, this technology provides a favorable profile of biocompatibility, stability, and safety, supported by its physicochemical characteristics.

    SUBLIME, VOLUME, AND DENSITY

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    Skin Architect Sublime Filler

    Facial Volume Correction

    Composition: 20 mg/mL cross-linked sodium hyaluronate

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    Skin Architect Filler Density

    Structural correction and volume restoration
    Composition:     23 mg/mL cross-linked sodium hyaluronate

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    Skin Architect Filler Volume

    Facial volume restoration
    Composition:     26 mg/mL cross-linked sodium hyaluronate

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    Three HA concentrations for a comprehensive treatment approach

    *La imagen tiene carácter ilustrativo y no sustituye las indicaciones, contraindicaciones ni los planos de implantación descritos en las IFU de cada producto.

    An intelligent and versatile portfolio designed to address all treatment indications:

    Its safety profile is associated with the high purity of the raw material, strict control of the manufacturing process, and its balanced rheological properties, which enable appropriate tissue integration and the achievement of natural-looking results.
    Common product features
    • Cross-linked hyaluronic acid of non-animal origin
    • Sterile gel, pyrogen-free
    • Viscoelastic, transparent, colorless, and biodegradable
    • Latex-free
    • 1.0 mL syringe with ±0.020 mL accuracy
    Clinical use
    • Injection performed by a doctor authorized according to local regulations
    • Requires knowledge of the anatomy of the area to be treated
    • Injection technique and depth depend on the area and the product
    Recommended volume

    Approximately up to 2 mL per application point (as per medical assessment)

    Efecto de relleno natural

    Acción regeneratibva sobre el tejido adiposo facial

    El bajo grado de reticulación de Skin Architect Fillers podría asociarse a una menor persistencia del producto.  

    La línea Skin Architect Filler gracias al ácido hialurónico de muy alto peso molecular, está diseñada para compensar este efecto mediante un abordaje biológico y regenerativo del tejido.

    Su capacidad de regeneración de la hipodermis favorece la estimulación de la diferenciación de preadipocitos en adipocitos y el aumento del contenido de lípidos dentro de los adipocitos. 

    Por lo tanto, promueve la regeneración de los compartimentos grasos faciales, cuyo tamaño disminuye durante el proceso del envejecimiento o en pérdidas abruptas de peso.

    Efecto de larga duración altamente sostenible 

    Aumento prolongado del volumen del tejido adiposo, compensando la degradación progresiva del ácido hialurónico sin necesidad de incrementarsugrado de reticulaciónni excesos de producto. El efecto visual del relleno biológico por la regeneración del tejido graso persiste más tiempo que el propio ácido hialurónico en el tejido.

    Estudio de seguridad

    Cuantificación de IL-8 para determinar la actividad antiinflamatoria

    El ácido hialurónico de 3000KDa tiene capacidad antiinflamatoria, disminuyendo la inflamación post tratamiento asociada a la técnica de inyección.

    Information for healthcare professionals

    Skin Architect Filler products should be used exclusively according to their complete instructions for use.
    A thorough clinical evaluation of the patient is recommended, and the risks and benefits should be considered in each case.
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    Request more information

    For additional information about Skin Architect Fillers or to address clinical questions related to their use, you can contact us.

    Contact for more information